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Lab outing

Lab outing

It has been a while since we last had an outing. We went bowling this time and had a great time. The boss was on a row!

#labouting #bowlingscientists

New Cooperation Pub with the Djamei Lab @effectomics

New Cooperation Pub with the Djamei Lab @effectomics

The Pleiades are a cluster of fungal effectors that inhibit host defenses

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009641

Biotrophic plant pathogens secrete effector proteins to manipulate the host physiology. Effectors suppress defenses and induce an environment favorable to disease development. In this paper we describe the functional characterization of the pleiades, a cluster of ten effector genes. Merope1, which is encoded in the Pleiades cluster, targets and promotes the auto-ubiquitination activity of RFI2, a conserved family of E3 ligases that regulates the production of PAMP-triggered ROS burst in plants.

Tansley insight on ubiquitin signalling is now out!

Tansley insight on ubiquitin signalling is now out!

Ubiquitin signalling: controlling the message of surface immune receptors

Microbial attack is first detected by immune receptors located at the plasma membrane. Their activation triggers a plethora of signalling cascades that culminate in the immune response. Ubiquitin and ubiquitin-like protein modifiers play key roles in controlling signalling amplitude and intensity, as well as in buffering proteome imbalances caused by pathogen attack. Here I highlight some of the important advances in the field, which are starting to reveal an intertwined and complex signalling circuitry, which regulates cellular dynamics and protein degradation to maintain homeostasis.

New Publication!

New Publication!

Excited to share our latest work in which we show that the “#Exocyst Subunit Exo70B2 is Linked to #Immunity and #Autophagy” maintaining cellular #homeostasis during enhanced secretory activity @ThePlantCell @UniFreiburg @TrujilloLab
This was quite the ordeal to get published, but we are proud about the result #exocyst #secretion #immunity #autophagy #phosphorylation #signalling #kinase #crosskindom #plants #yeast #homeostasis all in one story!

https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koaa022/6017825

New team member – Welcome Alaa!

New team member – Welcome Alaa!

Alaa joined us all the way from Palestine by way of Fukuoka (Japan). He invited us all to some delicious “Ramen” and “Udon” noodles. Carmen carefully inspected them carefully beforehand.

Thank you Alaa, it was oishi!

New Publication!

New Publication!

Check out this excellent cooperation paper with Ingo Heilmann from the University of Halle and Sabine Rosahl from the IPB “A phosphoinositide 5-phosphatase from Solanum tuberosum is activated by PAMP-treatment and may antagonize phosphatidylinositol 4,5-bisphosphate at Phytophthora infestans infection sites”

New Phytologist https://nph.onlinelibrary.wiley.com/doi/abs/10.1111/nph.16853