The German Research Foundation (DFG) awarded the prestigious Heisenberg prize to Marco to promote his research on ubiquitination, in particular investigating cross-talk with cellular signalling mediated by kinases. “We are humbled by this honour and deeply grateful for the support of the DFG”
We just published an Annual Review in Plant Biology on ” The Evolution and Functions of Plant U-Box Proteins: From Protein Quality Control to Signaling” were we explore the evolution of U-box proteins in the plant lineage all the way to structural details of E3 function. Please have a look here #Proteostasis #U-box #evolution #structure …
We are very proud of Carla who was accepted in the new round of the CORA Coaching Program at the University of Freiburg! Vice-President Prof. Dr. Sylvia Paletschek opened the Kick Off event on March 11th 🚀 CORA is a career advancement program focused on preparing female scientists for future leadership positions. GO Carla! #femaleleadership …
Join our team! We have a PhD position available. For more information, please follow this LINK
It has been a while since we last had an outing. We went bowling this time and had a great time. The boss was on a row! #labouting #bowlingscientists
We bid farewell to Bushra who will move the Spoel Lab @SpoelLab in Edinburgh, but will stick to ubiquitination. We wish you the best of luck!
The Pleiades are a cluster of fungal effectors that inhibit host defenses https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009641 Biotrophic plant pathogens secrete effector proteins to manipulate the host physiology. Effectors suppress defenses and induce an environment favorable to disease development. In this paper we describe the functional characterization of the pleiades, a cluster of ten effector genes. Merope1, which is …
Ubiquitin signalling: controlling the message of surface immune receptors Microbial attack is first detected by immune receptors located at the plasma membrane. Their activation triggers a plethora of signalling cascades that culminate in the immune response. Ubiquitin and ubiquitin-like protein modifiers play key roles in controlling signalling amplitude and intensity, as well as in buffering …
We wellcome Kai Clemens to our team! After working with moss, he will now try to develop crop plants with enhanced resistance to pathogens using components of the ubiquitin modification system.
We are very excited to see this article now published in PNAS. Happy to have been able to contribute! Great cooperation with Jacqui Monaghan’s Lab (Queen’s University, Canada). Check it out! https://www.pnas.org/content/118/19/e2024272118